| Date | Location | Result | |
| 03/06/06 | Murfreesboro, TN (Murphy Center) | Western Kentucky 80, Louisiana-Lafayette 72 | Box score |
| 03/05/06 | Murfreesboro, Tenn. (Murphy Center) | Louisiana-Lafayette 62, Troy 59 | Box score |
| 02/25/06 | Little Rock, Ark. (Jack Stephens Center) | Louisiana-Lafayette 69, Arkansas-Little Rock 59 | Box score |
| 02/23/06 | Lafayette, La. (CAJUNDOME) | Louisiana-Lafayette 71, Arkansas State 65 | Box score |
| 02/18/06 | Lafayette, La. (CAJUNDOME) | Louisiana-Lafayette 66, Stephen F. Austin 63 | Box score |
| 02/16/06 | New Orleans, La. (HPC) | Louisiana-Lafayette 76, New Orleans 69 | Box score |
| 02/11/06 | Troy, Ala. (Trojan Arena) | Troy 75, Louisiana-Lafayette 73 | Box score |
| 02/09/06 | Mobile, Ala. (Mitchell Center) | Louisiana-Lafayette 59, South Alabama 53 | Box score |
| 02/04/06 | Lafayette, La. (CAJUNDOME) | Louisiana-Lafayette 49, Denver 38 | Box score |
| 02/02/06 | Lafayette, La. (CAJUNDOME) | Louisiana-Lafayette 77, North Texas 58 | Box score |
| 01/28/06 | Murfreesboro, Tenn. (Murphy Center) | Middle Tennessee 73, Louisiana-Lafayette 59 | Box score |
| 01/26/06 | Bowling Green, Ky. (E.A. Diddle Arena) | Western Kentucky 94, Louisiana-Lafayette 81 | Box score |
| 01/23/06 | Lafayette, La. (CAJUNDOME) | Louisiana-Lafayette 60, New Orleans 53 | Box score |
| 01/21/06 | Miami, Fla. (Pharmed Arena) | Florida International 55, Louisiana-Lafayette 50 | Box score |
| 01/14/06 | Lafayette, La. (CAJUNDOME) | Troy 73, Louisiana-Lafayette 50 | Box score |
| 01/12/06 | Lafayette, La. (CAJUNDOME) | South Alabama 61, Louisiana-Lafayette 51 | Box score |
| 01/07/06 | Denver, Colo. (Magness Arena) | Denver 75, Louisiana-Lafayette 63 | Box score |
| 01/05/06 | Denton, Texas (The Super Pit) | North Texas 86, Louisiana-Lafayette 79 | Box score |
| 01/02/06 | Lafayette, La. (Blackham Coliseum) | Louisiana-Lafayette 76, Georgia State 70 | Box score |
| 12/29/05 | Reno, Nevada (Lawlor Events Center) | No. 20 Nevada 65, Louisiana-Lafayette 58 | Box score |
| 12/22/05 | Lafayette, La. (Blackham Coliseum) | Louisiana-Lafayette 89, McNeese State 77 | Box score |
| 12/17/05 | Baton Rouge, La. (Maravich Assembly Ctr) | LSU 81, Louisiana-Lafayette 62 | Box score |
| 12/15/05 | Lafayette, La. (Blackham Coliseum) | Louisiana-Lafayette 95, Oral Roberts 74 | Box score |
| 12/13/05 | Ruston, La. (Thomas Assembly Center) | Louisiana Tech 85, Louisiana-Lafayette 78 | Box score |
| 12/11/05 | El Paso, Texas (Don Haskins Center) | Louisiana-Lafayette 65, UTEP 59 | Box score |
| 12/03/05 | Lafayette, La. (Blackham Coliseum) | Charlotte 67, Louisiana-Lafayette 62 | Box score |
| 11/29/05 | Atlanta, Ga. (GSU Sports Arena) | Georgia State 76, Louisiana-Lafayette 61 | Box score |
| 11/22/05 | Knoxville, Tenn. (Thompson-Boling Arena) | Tennessee 83, Louisiana-Lafayette 76 | Box score |
| 11/18/05 | Carbondale, Ill. (SIU Arena) | Southern Illinois 65, Louisiana-Lafayette 47 | Box score |