| Date | Location | Result | |
| Nov 27, 2010 | Monroe, Louisiana | Louisiana 23, ULM 22 | Box score |
| Nov 20, 2010 | Lafayette, La. | FIU 38, Louisiana 17 | Box score |
| Nov 13, 2010 | Fort Lauderdale, FL | FAU 24, Louisiana 23 | Box score |
| Nov 06, 2010 | Oxford, Miss. | Ole Miss 43, Louisiana 21 | Box score |
| Oct 30, 2010 | Athens, Ohio | Ohio 38, Louisiana 31 | Box score |
| Oct 23, 2010 | Lafayette, La. | Western Kentucky 54, Louisiana 21 | Box score |
| Oct 16, 2010 | Troy, Alabama | TROY 31, Louisiana 24 | Box score |
| Oct 08, 2010 | Lafayette, La. | Oklahoma State 54, Louisiana 28 | Box score |
| Oct 02, 2010 | Denton, Texas | Louisiana 28, North Texas 27 | Box score |
| Sep 25, 2010 | Lafayette, La. | Middle Tennessee 34, Louisiana 14 | Box score |
| Sep 11, 2010 | Lafayette, La. | Louisiana 31, Arkansas State 24 | Box score |
| Sep 04, 2010 | Athens, Ga. | Georgia 55, Louisiana 7 | Box score |